Similipal Biosphere Reserve (SBR) is situated in the district of Mayurbhanj, Odisha. It forms the major part of Eastern Ghats having rich floral diversity. SBR is inhabited by many tribal communities too. They are in habit of using the wild phytoresources against different microbial infections. Wild cucurbits are prime components of the phytoresources of SBR. Keeping this in view, four wild cucurbits (Trichosanthes tricuspidata, Diplocyclos palmatus, Cucumis melo, Trichosanthes cucumerina) were collected from SBR and experimented for their antibacterial activities against five selected bacterial strains (Streptococcus mutans - MTCC 497, Streptococcus pyogenes - MTCC 1926, Vibrio cholerae - MTCC 3906, Shigella flexneri - MTCC 1457 and Salmonella typhi - MTCC 1252). The MIC (minimum inhibitory concentration) of the extracts was determined using broth dilution assay. Results revealed that the methanol extract of T. tricuspidata fruits showed lowest MIC values against S. pyogenes whereas the acetone and methanol extract of C. melo fruits showed lowest MIC values against S. mutans. The paper highlights a comparative account of antibacterial potential of wild cucurbits collected from SBR and activity of the extracts against specific bacterial species.
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