Alstonia scholaris (L.) R. Br., a tropical plant belonging to Apocynaceae family had been a fruitful traditional medicine in ayurveda and was used in several ailments. Alstonia scholaris is rich in phytochemicals like alkaloids, terpenoids, flavonoids, iridoids and essential oils. These phytochemicals are isolated from roots, stem, bark, fruits, flowers and leaves of Alstonia scholaris. The pharmacological aspect of Alstonia scholaris shows its greater potential in treatment of bacterial and viral infection, inflammatory diseases, ulcers, rheumatism, diarrhoea, hyperuricemia, diabetes, malaria, neural and cardiovascular diseases. Apart from these, Alstonia scholaris have been found to show antioxidant, immunomodulatory, antidepressant, analgesic and anticancer properties including cytotoxicity against various cancers in vitro and in vivo conditions. However, even after showing such pharmacological relevance, the clinical and pre-clinical studies of Alstonia scholaris is negligible. This review provides insights to the existing knowledge of Alstonia scholaris and its requisite in further research, so that it can be used as a therapeutic drug in near future.
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