Leaves of Ichnocarpus frutescens (L.) R.Br. were collected from the Gahamakhunti of Dhenkanal districts, Odisha, commonly called as swamnai. The leaves were extracted with hexane, chloroform, diethyl ether, methanol and water for the in vitro study of antimicrobial property. The chloroform extract was found to be more active against Pseudomonas putida and Aspergillus fumigatus. Methanol extract was found to possess maximum antimicrobial activity against most of the test pathogens but maximum effect was found against Bacillus sphaericus (15 mm), Bacillus polymyxa (14 mm), Aspergillus niger (25 mm) and A. fumigatus (22 mm) and minimum activity was found against Bacillus circulans. Negative response was found against Escherichia coli and Pseudomonas putida. In case of chloroform extract of I. frutescens, maximum inhibition (21 mm) was found against Pseudomonas putida whereas minimum activity (5 mm) was found against Bacillus circulans. The diethyl ether extract did not show any response against the test pathogens except Bacillus sphaericus (15 mm) and Bacillus circulans (11 mm). A maximum inhibition zone of 17 mm and minimum of 8 mm was found against Bacillus polymyxa and Bacillus sphaericus, respectively. The present screening result demonstrated that the methanol and chloroform extracts of leaf of the fiber yielding plant I. frutescens has potent antibacterial as well as antifungal activity and the studied plant may be a new source for novel antimicrobial compound discovery for treating disease causing human pathogens.
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